What We Do

We consistently enroll among the top 5% of all participating sites for clinical studies including NAFLD, NASH, MRSA, ABSSSI, pain, sepsis, community-acquired pneumonia, hospital-acquired pneumonia, diabetes, dermatology, vaccines, CV, influenza, and many others.

Through our corporate-wide commitment to research excellence, it is our goal to improve the process that will bring new medicines to our global community. We will settle for nothing less than changing the paradigm of clinical trials. We will do so by continuing to be on the progressive edge of efficient innovation to become the industry leader.

Meet Our Team

Hoa Tuyet Bui, M.D. - Principal Investigator
Carrie Cardenas, M.D. - Principal Investigator
Heidi Kabler, M.D. - Principal Investigator
Steve Mannis, M.D. - Principal Investigator
Paul Manos, D.O. - Assistant Medical Director
Alison McManus DNP, FNP-BC - Principal Investigator
J. Scott Overcash, M.D. - Principal Investigator
Elliot Shin, M.D. - Principal Investigator
Sandra Win, M.D., M.S. - Principal Investigator

Physicians/Principal Investigators

All clinical staff are trained and certified in Good Clinical Practice, the Health Insurance Portability and Accountability Act, and on the NIH Protecting Human Research Participants course.

 
Maurizio Bonacini, M.D.
Principal Investigator

Dr. Bonacini serves as a Principal Investigator in San Francisco. Dr. Bonacini received his medical degree, Magna cum Laude, at Universite Catholique de Louvain School of Medicine, in Brussels, Belgium. He completed his residency in 1989 at the University of Southern California, and is board certified in Internal Medicine, Gastroenterology, and Transplant Hepatology. Dr. Bonacini’s research experience includes, but is not limited to: hepatitis; anemia; HIV; liver disease; and other infectious diseases. He has clinical experience in experience in general medicine including: pain management; cardiovascular diseases; and dermatology.

 
Hoa Tuyet Bui, M.D. 
Principal Investigator
 
Dr. Bui serves as a Principal Investigator in Las Vegas. Dr. Bui received her medical degree at University of Missouri School of Medicine, and is board certified in Family Medicine. She is also BLS, ACLS and PALS certified. Her research experience includes, but is not limited to: pneumonia; skin infections; hepatitis; influenza; diabetes; and other infectious diseases. She has clinical experience in general medicine including: pain management; cardiovascular diseases; and dermatology.
 
Carrie Cardenas, M.D.
Principal Investigator
 
Dr. Cardenas serves as a Principal Investigator in La Mesa. Dr. Cardenas received her bachelor’s degree at San Diego State University, medical degree at UC San Francisco, and completed an internal medicine residency at Stanford University Hospital. Dr. Cardenas’ research experience includes, but is not limited to: pneumonia; skin infections; hepatitis; influenza; diabetes; and other infectious diseases.  She has clinical experience in general medicine including: pain management; cardiovascular diseases; and
dermatology.
 
Heidi Kabler, M.D.
Principal Investigator
 
Dr. Kabler joined eStudySite in 2012 and serves as a Principal Investigator at our Las Vegas site. Dr. Kabler completed her Bachelor of Science degree, graduating summa cum laude, from Duquesne University in Pittsburgh, PA. She earned her medical degree from Wright State University School of Medicine in Dayton, Ohio. She went on to complete her residency in Emergency Medicine at Wright State University where she was also named Chief Resident. Dr. Kabler is board certified in Emergency Medicine, and after residency she moved to Las Vegas, NV to practice Emergency Medicine with Fremont Emergency Services. Her clinical research at eStudySite includes Complicated Skin Infections, Clostridium Difficile,  Influenza, Hepatitis C, Diabetes, and Oral Nutritional Supplements.
 
Steven Mannis, M.D.
Principal Investigator
 
Dr. Mannis serves as a Principal Investigator at our Oceanside site and has been an emergency medicine physician for over 25 years. Dr. Mannis also serves as medical director at Vista Detention Facility.  Dr. Mannis received his bachelor’s degree at University of California Santa Cruz, medical degree at Autonomous University of Guadalajara, and completed an emergency medicine residency in Toledo, Ohio at St. Vincent’s and Toledo Hospital. Dr. Mannis’ research experience includes, but is not limited to: skin infections; pneumonia; hepatitis; influenza; diabetes; and other infectious diseases.  He has clinical experience in general medicine including: hypertension; pain management; cardiovascular
diseases; dermatology; and pediatrics. 
 
Paul Manos, D.O.
Principal Investigator

Dr. Manos, one of the original founders of eStudySite in 1999, currently serves as Assistant Medical Director, co-directing clinical research studies for the company and as a Principal Investigator at our Oceanside site. He is Director of Emergency Services at Paradise Valley Hospital, where he has been an Emergency Staff Physician and Associate Medical Director. He was also Staff Physician at Sharp Chula Vista Hospital. Dr. Manos received a Bachelor Science degree at the University of Southern California and earned his Medical Degree in 1993 from Midwestern University Chicago College of Osteopathic Medicine. He completed his Residency at Wayne State University, The Detroit Medical Center – Grace Hospital in 1997.

 
Alison McManus DNP, FNP-BC
Principal Investigator
 
Dr. McManus joined eStudySite in 2007 as a Sub-Investigator and subsequently assumed a role of Principal Investigator at our Chula Vista site.  Alison completed her Masters in Nursing as a Nurse Practitioner at the University of San Diego and her Doctorate of Nursing Practice at Rush University in Chicago.  Alison is a Board Certified Family Nurse Practitioner and a Certified Emergency Nurse.  She has over 20 years of experience in the Emergency Department.  Her clinical research experience includes; complicated skin infections, community acquired pneumonia, influenza, anemia, diabetes, vaccines, and hepatitis C.
 
J. Scott Overcash, M.D.
Principal Investigator
 
Dr. Overcash joined eStudySite in 2012 and is a Principal Investigator at our Chula Vista site.  Dr. Overcash is a board certified Emergency Physician with over 10 years of clinical and research experience. He attended the University of North Carolina School of Medicine where he obtained his M.D. degree and completed their highly ranked Emergency Medicine residency program. Dr. Overcash is a Diplomate of the American Board of Emergency Medicine, a Fellow of the American Board of Emergency Medicine, board certified by the American Academy of Anti-Aging, and an active member of the Association of Clinical Research Professionals. His work has been published in national peer reviewed journals including the New England Journal of Medicine. 
 
Elliot Shin, M.D.
Principal Investigator
 
Dr. Shin serves as a Principal Investigator at our Las Vegas site. He graduated from Rutgers University as a Henry Rutgers Scholar in 1991, obtained a master’s degree in Nuclear Physics at Rosalind Franklin University of Health Sciences/The Chicago Medical School where he also received his medical degree in 2000. He then completed his residency training in 2003 at In His Image Family Practice Residency Program where he was also ordained as a medical missionary. Dr. Shin is a board certified family physician. Dr. Shin founded Operation H.O.P.E., Inc. (Helping Other People Everywhere) in October of 2009 to invite the public to join with him in providing comprehensive solutions to the homeless and underprivileged populations worldwide. Since 2010, HOPE Clinic has seen over 14,000 uninsured low-income patients and continues to provide service and support to the community.
 
Michael Waters, M.D.
Principal Investigator
 
Dr. Waters serves as a Principal Investigator at our Chula Vista site. Dr. Waters received his medical degree at UC Irvine School of Medicine, and is board certified in Emergency Medicine. His research experience includes, but is not limited to: pneumonia; skin infections; hepatitis; influenza; diabetes; and other infectious diseases.  He has clinical experience in general medicine including: pain management; cardiovascular diseases; and dermatology. 
 
Sandra Win, M.D., M.S.
Principal Investigator
 

Dr. Win, is a Principal Investigator at our San Francisco site (formerly Quest Clinical Research). Dr. Win is a Diplomate of the American Board of Family Medicine and holds further certifications in HIV and Chronic Liver Disease, including Hepatitis B and C. She completed her residency training through U.C. Irvine College of Medicine. In addition, she is a medical epidemiologist and biostatistician certified by Stanford University School of Medicine. Her professional interests include infectious disease - in particular, HIV and Hepatitis B & C - public health, community education, and medical education. She has volunteered as a clinical preceptor and instructor for medical students and resident physicians through UCSF School of Medicine, and she is on the speaker’s panel for organizations such as the American Liver Foundation and the Hepatitis B Foundation.

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