Ulcerative Colitis (UC) is an Inflammatory Bowel Disease that happens when your immune system makes a mistake. Normally your immune system attacks sickness in your body, like the common cold, but when you have UC, white blood cells that usually protect you from illness attack the lining of your colon instead. This causes irritation, inflammation, and ulcers in the lining of your large intestine, or colon.

UC is different from other diseases with similar symptoms, like Crohn’s Disease and Irritable Bowel Syndrome. There’s no cure, and people usually have symptom flare-ups off and on for life. The right treatment can help minimize the flare-ups of this condition.



Crohn’s disease affects both men and women and can occur at any age, though it is most prevalent in adolescents and young adults.

When you are diagnosed with Crohn's, the GI tract mistakes harmless bacteria as invaders to the immune system. What happens is cells travel out of the blood to the intestines causing inflammation. The inflammation persists, which then leads to chronic inflammation, ulceration, thickening of the intestinal wall, and eventually causes symptoms as seen below.

Crohn’s can be hereditary, so if you or a relative have the disease, another family member has a significant chance of developing Crohn’s as well.



  • Bloody diarrhea/pus in your stool
  • Cramping belly pain 
  • Sudden urges to empty your colon right away
  • Not feeling hungry
  • Weight loss
  • Feeling tired 
  • Fever
  • Dehydration
  • Join pain or soreness 
  • Canker sores
  • Eye pain when you look at a bright light
  • Anemia  
  • Skin sores
  • Persistent Diarrhea
  • Rectal bleeding
  • Urgent need to move bowels
  • Abdominal cramps and pain
  • Sensation of incomplete evacuation
  • Constipation 

eStudySite engages in investigative clinical trials of medications treating Ulcerative Colitis and Crohn's Disease. Qualified subjects participating in a trial receive study-related medical evaluations  and the investigative study medication at no cost, and may be eligible to receive financial compensation for time and travel cost.

If you suffer from Ulcerative Colitis OR Crohn's Disease and would like to learn more, or volunteer for a study,  please fill out the form to the right, or call us at 619-704-2750.

If you know someone suffering from Ulcerative Colitis OR Crohn's who may want to learn more or volunteer, you can let us know by clicking the button below.
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